肖传国的成功

Beaumont sees results in nation‘s 1st urinary nerve rewiring surgeries for spina bifida patients
04/17/2008
View photos from the press conference.
Seven children from across the United States are gaining bladdercontrol through a revolutionary, first-in-the-nation nerve reroutingsurgery for patients with spina bifida. The surgeries were conducted in2007 at Beaumont Hospital in Royal Oak, Mich.
The children previously required the insertion of a catheter toempty their bladder or endured significant incontinence. But as aresult of the surgery, they are beginning to void on their own and arealso seeing improvement in bowel function. Initially they signaled thebladder to urinate by scratching or pinching their leg or buttocks.But, remarkably, in most patients the brain was able to take over andcontrol urination normally.
This will allow them to attend school without being catheterizedand to play with other children without the embarrassment of soilingthemselves. It also means fewer urinary tract infections resulting fromcatheterization, and reduces their need for antibiotics for infectioncontrol.
Kenneth Peters, M.D., chairman,
Urology department,
Beaumont, Royal Oak.
"These are still considered early results but we are excited to seethem," says Kenneth Peters, M.D., chairman of the Urology department atBeaumont, Royal Oak. "It‘s still too early to see results on the twoadult patients with spinal cord injuries who also had the surgery."
Results of Dr. Peters‘ research on nerve rerouting surgery are tobe presented in May at the American Urological Association annualmeeting.
Local philanthropists J. Peter and Florine Ministrelli of WestBloomfield, Mich. underwrote the cost of the surgeries. They have alsofunded the Ministrelli Program for Urology Research and Education atBeaumont, which enables Beaumont to continue its leadership through thepurchase of equipment, the expansion of education and research effortsand bringing innovative treatments to patients.
In spinal cord injury and spina bifida, the nerves that control thebladder and sphincter are damaged. People cannot urinate without theuse of a catheter or are constantly wet. Most experience recurrenturinary tract infections. Also, backup of urine into the kidneys candamage these delicate organs. As a result, kidney dialysis ortransplant may be required.
The research at Beaumont uses a spinal surgery pioneered in Chinato redirect nerves from the leg to the bladder to gain better controlof urination. Beaumont is the only U.S. hospital performing thissurgery, and patients have traveled from as far as Utah andPennsylvania to have it. The Chinese doctor who developed the surgery,Chuan-Guo Xiao, M.D., reports an almost 90-percent success rate and anaverage time for results of 12-24 months after surgery.
"In a stunning reversal of the exchange of information andtechnology, which typically originates in the United States and isexported to countries like China, we are able to offer these patientsurinary function and dramatically improved their quality of life," saysDr. Peters. "We are grateful to Dr. Xiao and to the patients in thisstudy who are truly medical pioneers."
Chinese surgeon Chuan-Guo
Xiao, M.D. and Dr. Peters.
Possible side effects of the surgery include mild postoperativespinal fluid leakage, lower extremity weakness and headache. Recentchanges in the surgical technique have dramatically decreased theincidence of these complications. Standard risks associated with anysurgery may include bleeding and infection.
The surgical team that worked with Dr. Peters at Beaumont includesDr. Xiao; Ananias Diokno, M.D., Beaumont Hospitals‘ chief medicalofficer; and urologist Jose Gonzalez, M.D.
"Nerve rerouting is an example of Beaumont‘s leadership intranslational research that applies research results to clinical carethat is life changing for our patients," says Dr. Diokno
Call study coordinator Cindy Turzewski, R.N., at 248-551-3355 ore-mail her at Cynthia.turzewski@beaumont.edu, for more information onthe nerve rerouting research.
Beaumont‘s 1,061-bed hospital in Royal Oak is a major academic,research and referral center with Level I trauma designation. It ranksfirst in the United States for inpatient admissions and second forsurgical volume. Beaumont, Royal Oak is named in nine medicalspecialties on the U.S. News & World Report‘s "America‘s BestHospitals" list, ranking 31st as a top hospital for urology.
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