神马文学网Definition of Homolog, Ortholog and Paralog
来源：百度文库 编辑：神马文学网 时间：2024/04/29 20:08:25
It was suggested that I might want toprovide definitions which made the difference between these termsclear. These definitions are provided here.
Homolog A gene related to a second gene by descent from a common ancestral DNA sequence. The term, homolog, may apply to the relationship between genes separated by the event of speciation (see ortholog) or to the relationship betwen genes separated by the event of genetic duplication (see paralog).
Ortholog Orthologs are genes in different species that evolved from a common ancestral gene by speciation. Normally, orthologs retain the same function in the course of evolution. Identification of orthologs is critical for reliable prediction of gene function in newly sequenced genomes. (See also Paralogs.).
Speciation Speciation is the origin of a new species capable of making a living in a new way from the species from which it arose. As part of this process it has also aquired some barreir to genetic exchage with the parent species.
Paralog Paralogs are genes related by duplication within a genome. Orthologs retain the same function in the course of evolution, whereas paralogs evolve new functions, even if these are related to the original one.
See the following NCBI diagramOrthology which shows the relationship between the three terms.
Homolog A gene related to a second gene by descent from a common ancestral DNA sequence. The term, homolog, may apply to the relationship between genes separated by the event of speciation (see ortholog) or to the relationship betwen genes separated by the event of genetic duplication (see paralog).
Ortholog Orthologs are genes in different species that evolved from a common ancestral gene by speciation. Normally, orthologs retain the same function in the course of evolution. Identification of orthologs is critical for reliable prediction of gene function in newly sequenced genomes. (See also Paralogs.).
Speciation Speciation is the origin of a new species capable of making a living in a new way from the species from which it arose. As part of this process it has also aquired some barreir to genetic exchage with the parent species.
Paralog Paralogs are genes related by duplication within a genome. Orthologs retain the same function in the course of evolution, whereas paralogs evolve new functions, even if these are related to the original one.
See the following NCBI diagramOrthology which shows the relationship between the three terms.
Definition of Homolog, Ortholog and Paralog(ncbi)
Definition of Homolog, Ortholog and Paralog
A Definition of a PLE
mercantilism: Definition and Much More from A...
sonar: Definition and Much More from Answers....
Christmas: Definition and Much More From Answers
Byte Alignment and Ordering in Message Definition
Definition & Core Principles of EE(Experiential Education)
dredger - Definition of dredger at YourDictio...
3G: Definition and Much More From Answers.com
wikipedia | Christmas: Definition and Much More From Answers.com
netizen: Definition and Much More From Answers.com
amino acid: Definition and Much More from Answers.com
acetylcholine: Definition and Much More from Answers.com
titanium dioxide: Definition and Much More from Answers.com
hypnotism: Definition and Much More from Answers.com
liquid-crystal display: Definition and Much More from Answers.com
LED: Definition and Much More from Answers.com
Chicken: Definition and Much More from Answers.com
dredger - definition of dredger by the Free O...
déjà vu: Definition and Much More from Answers.com
STRATEGY AND TACTICS OF THE CLASS STRUGGLE
BlogHer and the culture of generosity
An Outline Of Reading Theory And Practice